diff --git a/src/libs/NumberFormatUtils/index.ts b/src/libs/NumberFormatUtils/index.ts
index cf04fa6eca56..02bb14b29eed 100644
--- a/src/libs/NumberFormatUtils/index.ts
+++ b/src/libs/NumberFormatUtils/index.ts
@@ -1,10 +1,9 @@
-import intlPolyfill from '@libs/IntlPolyfill';
 import memoize from '@libs/memoize';
 import CONST from '@src/CONST';
 import type Locale from '@src/types/onyx/Locale';
+import initPolyfill from './intlPolyfill';
 
-// Polyfill the Intl API if locale data is not as expected
-intlPolyfill();
+initPolyfill();
 
 const MemoizedNumberFormat = memoize(Intl.NumberFormat, {maxSize: 10, monitoringName: 'NumberFormatUtils'});
 
diff --git a/src/libs/NumberFormatUtils/intlPolyfill.ios.ts b/src/libs/NumberFormatUtils/intlPolyfill.ios.ts
new file mode 100644
index 000000000000..4745284c0b61
--- /dev/null
+++ b/src/libs/NumberFormatUtils/intlPolyfill.ios.ts
@@ -0,0 +1,10 @@
+import intlPolyfill from '@libs/IntlPolyfill';
+
+// On iOS, polyfills from `additionalSetup` are applied after memoization, which results in incorrect cache entry of `Intl.NumberFormat` (e.g. lacking `formatToParts` method).
+// To fix this, we need to apply the polyfill manually before memoization.
+// For further information, see: https://github.com/Expensify/App/pull/43868#issuecomment-2217637217
+const initPolyfill = () => {
+    intlPolyfill();
+};
+
+export default initPolyfill;
diff --git a/src/libs/NumberFormatUtils/intlPolyfill.ts b/src/libs/NumberFormatUtils/intlPolyfill.ts
new file mode 100644
index 000000000000..31fedd6a01b6
--- /dev/null
+++ b/src/libs/NumberFormatUtils/intlPolyfill.ts
@@ -0,0 +1,2 @@
+const initPolyfill = () => {};
+export default initPolyfill;
diff --git a/src/setup/index.ts b/src/setup/index.ts
index 6a0e2c4413c3..8c5a32ea170f 100644
--- a/src/setup/index.ts
+++ b/src/setup/index.ts
@@ -1,5 +1,6 @@
 import {I18nManager} from 'react-native';
 import Onyx from 'react-native-onyx';
+import intlPolyfill from '@libs/IntlPolyfill';
 import {setDeviceID} from '@userActions/Device';
 import initLocale from '@userActions/Locale';
 import initOnyxDerivedValues from '@userActions/OnyxDerived';
@@ -63,6 +64,9 @@ export default function () {
     I18nManager.allowRTL(false);
     I18nManager.forceRTL(false);
 
+    // Polyfill the Intl API if locale data is not as expected
+    intlPolyfill();
+
     // Perform any other platform-specific setup
     platformSetup();