diff --git a/.github/workflows/build_pymeos_cffi.yml b/.github/workflows/build_pymeos_cffi.yml
new file mode 100644
index 00000000..6eaf8b2d
--- /dev/null
+++ b/.github/workflows/build_pymeos_cffi.yml
@@ -0,0 +1,219 @@
+name: Build PyMEOS CFFI
+
+on:
+  create:
+    tags:
+      - "pymeos-cffi-[0-9]+.[0-9]+.[0-9]+*"
+
+jobs:
+  build_sdist:
+    name: Build PyMEOS CFFI source distribution
+    runs-on: ubuntu-latest
+    steps:
+      - name: Checkout
+        uses: actions/checkout@v4
+
+      - name: Install Python
+        uses: actions/setup-python@v5
+        with:
+          python-version: 3.8
+          cache: "pip"
+
+      - name: Setup pip
+        run: |
+          python -m pip install --upgrade pip
+          python -m pip install build
+
+      - name: Build sdist
+        working-directory: pymeos_cffi
+        run: |
+          python -m build -s
+          ls -l dist
+
+      - uses: actions/upload-artifact@v4
+        with:
+          name: pymeos_cffi-sdist
+          path: ./pymeos_cffi/dist/pymeos_cffi-*.tar.gz
+
+  build_wheels:
+    name: Build PyMEOS CFFI for ${{ matrix.os }}
+    runs-on: ${{ matrix.os }}
+    strategy:
+      fail-fast: false
+      matrix:
+        os: [ ubuntu-latest, macos-13, macos-14 ]
+        include:
+          - ld_prefix: "/usr/local"
+          - os: macos-14
+            ld_prefix: "/opt/homebrew"
+
+    steps:
+      - name: Checkout
+        uses: actions/checkout@v4
+
+      - name: Update brew
+        if: matrix.os == 'macos-13'
+        # Necessary to avoid issue with macOS runners. See
+        # https://github.com/actions/runner-images/issues/4020
+        run: |
+          brew reinstall python@3.12 || brew link --overwrite python@3.12
+          brew reinstall python@3.11 || brew link --overwrite python@3.11
+          brew update
+
+      - name: Get dependencies from homebrew (cache)
+        uses: tecolicom/actions-use-homebrew-tools@v1
+        if: runner.os == 'macOS'
+        with:
+          tools: cmake libpq proj json-c gsl geos
+
+      - name: Get PROJ version
+        id: proj_version
+        if: runner.os == 'macOS'
+        run: |
+          proj_version=$(brew list --versions proj)
+          proj_version=${proj_version#* }
+          echo "proj_version=$proj_version" >> $GITHUB_OUTPUT
+
+      - name: Install MEOS
+        if: runner.os == 'macOS'
+        run: |
+          git clone --depth 1 https://github.com/MobilityDB/MobilityDB
+          mkdir MobilityDB/build
+          cd MobilityDB/build
+          cmake .. -DMEOS=on
+          make -j
+          sudo make install
+
+      - name: Setup Python
+        uses: actions/setup-python@v5
+
+      - name: Install cibuildwheel
+        run: python -m pip install cibuildwheel==2.17.0
+
+      - name: Set PROJ_DATA (macOS)
+        if: runner.os == 'macOS'
+        run: |
+          PROJ_DATA=${{ matrix.ld_prefix }}/Cellar/proj/${{ steps.proj_version.outputs.proj_version }}/share/proj
+          echo "PROJ_DATA=$PROJ_DATA" >> $GITHUB_ENV
+
+      - name: Set PROJ_DATA and JSON-C path (Linux)
+        if: runner.os == 'Linux'
+        run: |
+          PROJ_DATA=/usr/proj81/share/proj
+          echo "PROJ_DATA=$PROJ_DATA" >> $GITHUB_ENV
+          echo "LD_LIBRARY_PATH=$LD_LIBRARY_PATH:/usr/local/lib64" >> $GITHUB_ENV
+
+      - name: Build wheels
+        working-directory: pymeos_cffi
+        run: |
+          export LD_LIBRARY_PATH=$LD_LIBRARY_PATH:${{ matrix.ld_prefix }}/lib
+          export DYLD_LIBRARY_PATH=$DYLD_LIBRARY_PATH:${{ matrix.ld_prefix }}/lib
+          export PACKAGE_DATA=1
+          python -m cibuildwheel --output-dir wheelhouse
+        env:
+          # Disable PyPy builds on Linux since shapely has no built distributions for them
+          # Disable builds on musllinux
+          # Disable builds in linux architectures other than x86_64
+          CIBW_SKIP: "pp*-manylinux* *musllinux*"
+          CIBW_ARCHS_LINUX: "x86_64"
+          CIBW_ENVIRONMENT_PASS_LINUX: PACKAGE_DATA LD_LIBRARY_PATH PROJ_DATA
+          CIBW_BEFORE_ALL_LINUX: >
+            yum -y install https://download.postgresql.org/pub/repos/yum/reporpms/EL-7-x86_64/pgdg-redhat-repo-latest.noarch.rpm &&
+            yum -y update &&
+            yum -y install gcc gcc-c++ make cmake postgresql13-devel proj81-devel geos39-devel gsl-devel &&
+            git clone --branch json-c-0.17 --depth 1 https://github.com/json-c/json-c &&
+            mkdir json-c-build &&
+            cd json-c-build &&
+            cmake ../json-c &&
+            make &&
+            make install &&            
+            git clone --depth 1 https://github.com/MobilityDB/MobilityDB &&
+            mkdir MobilityDB/build &&
+            cd MobilityDB/build &&
+            cmake .. -DMEOS=on -DGEOS_INCLUDE_DIR=/usr/geos39/include/ -DGEOS_LIBRARY=/usr/geos39/lib64/libgeos_c.so -DGEOS_CONFIG=/usr/geos39/bin/geos-config -DPROJ_INCLUDE_DIRS=/usr/proj81/include/ -DPROJ_LIBRARIES=/usr/proj81/lib/libproj.so &&
+            make -j &&
+            make install
+
+          CIBW_TEST_COMMAND: "python -c \"from pymeos_cffi import meos_initialize, meos_finalize; meos_initialize('UTC'); meos_finalize()\""
+
+      - uses: actions/upload-artifact@v4
+        with:
+          name: pymeos_cffi-wheels-${{ matrix.os }}
+          path: ./pymeos_cffi/wheelhouse/*.whl
+
+  test_wheels:
+    name: Test PyMEOS CFFI wheel - Python ${{ matrix.python-version }} on ${{ matrix.os }}
+    needs: build_wheels
+    runs-on: ${{ matrix.os }}
+    strategy:
+      fail-fast: false
+      matrix:
+        python-version: [ "3.8", "3.9", "3.10", "3.11", "3.12" ]
+        os: [ ubuntu-latest, macos-13, macos-14 ]
+        exclude:
+          # Necessary due to issue with macOS runners. See
+          # https://github.com/actions/setup-python/issues/808
+          # Can be removed once this PR is merged:
+          # https://github.com/actions/python-versions/pull/259
+          - os: macos-14
+            python-version: "3.8"
+          - os: macos-14
+            python-version: "3.9"
+
+    steps:
+      - name: Checkout
+        uses: actions/checkout@v4
+
+      - name: Download wheels
+        uses: actions/download-artifact@v4
+        with:
+          name: pymeos_cffi-wheels-${{ matrix.os }}
+          path: ./pymeos_cffi_wheels
+
+      - name: Set up Python ${{ matrix.python-version }}
+        uses: actions/setup-python@v5
+        with:
+          python-version: ${{ matrix.python-version }}
+          cache: "pip"
+
+      - name: Install PyMEOS dependencies
+        run: |
+          python -m pip install --upgrade pip
+          pip install -f ./pymeos_cffi_wheels pymeos_cffi
+          pip install -r pymeos/dev-requirements.txt
+
+      - name: Test PyMEOS with pytest
+        working-directory: pymeos
+        run: pytest
+
+  upload_pypi:
+    name: Upload to PyPI
+    needs: [ test_wheels, build_sdist ]
+    runs-on: ubuntu-22.04
+    steps:
+      - uses: actions/download-artifact@v4
+        with:
+          path: ./dist
+          merge-multiple: true
+
+      - uses: pypa/gh-action-pypi-publish@release/v1
+        with:
+          user: __token__
+          password: ${{ secrets.TEST_PYPI_API_TOKEN }}
+          repository_url: https://test.pypi.org/legacy/
+          skip_existing: true
+
+  create_release:
+    name: Create GitHub Release
+    needs: [ test_wheels, build_sdist ]
+    runs-on: ubuntu-22.04
+    steps:
+      - uses: actions/download-artifact@v4
+        with:
+          path: ./dist
+          merge-multiple: true
+
+      - name: Create Release
+        uses: softprops/action-gh-release@v2
+        with:
+          files: ./dist/*
\ No newline at end of file
diff --git a/pymeos_cffi/pymeos_cffi/builder/build_pymeos.py b/pymeos_cffi/pymeos_cffi/builder/build_pymeos.py
index 0ffb0d4e..92a2bc35 100644
--- a/pymeos_cffi/pymeos_cffi/builder/build_pymeos.py
+++ b/pymeos_cffi/pymeos_cffi/builder/build_pymeos.py
@@ -1,5 +1,4 @@
-import platform
-import sys
+import os
 
 from cffi import FFI
 
@@ -12,27 +11,13 @@
 
 
 def get_library_dirs():
-    if sys.platform == "linux":
-        return ["/usr/local/lib"]
-    elif sys.platform == "darwin":
-        if platform.processor() == "arm":
-            return ["/opt/homebrew/lib"]
-        else:
-            return ["/usr/local/lib"]
-    else:
-        raise NotImplementedError("Unsupported platform")
+    paths = ["/usr/local/lib", "/opt/homebrew/lib"]
+    return [path for path in paths if os.path.exists(path)]
 
 
 def get_include_dirs():
-    if sys.platform == "linux":
-        return ["/usr/local/include"]
-    elif sys.platform == "darwin":
-        if platform.processor() == "arm":
-            return ["/opt/homebrew/include"]
-        else:
-            return ["/usr/local/include"]
-    else:
-        raise NotImplementedError("Unsupported platform")
+    paths = ["/usr/local/include", "/opt/homebrew/include"]
+    return [path for path in paths if os.path.exists(path)]
 
 
 ffibuilder.set_source(
@@ -41,7 +26,7 @@ def get_include_dirs():
     libraries=["meos"],
     library_dirs=get_library_dirs(),
     include_dirs=get_include_dirs(),
-)  # library name, for the linker
+)
 
 if __name__ == "__main__":  # not when running with setuptools
     ffibuilder.compile(verbose=True)
diff --git a/pymeos_cffi/pymeos_cffi/builder/build_pymeos_functions_modifiers.py b/pymeos_cffi/pymeos_cffi/builder/build_pymeos_functions_modifiers.py
index 2cf1093e..7dcd98b5 100644
--- a/pymeos_cffi/pymeos_cffi/builder/build_pymeos_functions_modifiers.py
+++ b/pymeos_cffi/pymeos_cffi/builder/build_pymeos_functions_modifiers.py
@@ -42,6 +42,14 @@ def textset_make_modifier(function: str) -> str:
 
 def meos_initialize_modifier(_: str) -> str:
     return """def meos_initialize(tz_str: "Optional[str]") -> None:
+    
+    if "PROJ_DATA" not in os.environ and "PROJ_LIB" not in os.environ:
+        proj_dir = os.path.join(os.path.dirname(__file__), "proj_data")
+        if os.path.exists(proj_dir):
+            # Assume we are in a wheel and the PROJ data is in the package
+            os.environ["PROJ_DATA"] = proj_dir
+            os.environ["PROJ_LIB"] = proj_dir
+    
     tz_str_converted = tz_str.encode('utf-8') if tz_str is not None else _ffi.NULL
     _lib.meos_initialize(tz_str_converted, _lib.py_error_handler)"""
 
diff --git a/pymeos_cffi/pymeos_cffi/builder/templates/functions.py b/pymeos_cffi/pymeos_cffi/builder/templates/functions.py
index 992dfd74..e79c4f88 100644
--- a/pymeos_cffi/pymeos_cffi/builder/templates/functions.py
+++ b/pymeos_cffi/pymeos_cffi/builder/templates/functions.py
@@ -1,4 +1,6 @@
 import logging
+import os
+
 from datetime import datetime, timedelta, date
 from typing import Any, Tuple, Optional, List
 
diff --git a/pymeos_cffi/pymeos_cffi/functions.py b/pymeos_cffi/pymeos_cffi/functions.py
index c50e0ff5..4151409a 100644
--- a/pymeos_cffi/pymeos_cffi/functions.py
+++ b/pymeos_cffi/pymeos_cffi/functions.py
@@ -1,4 +1,6 @@
 import logging
+import os
+
 from datetime import datetime, timedelta, date
 from typing import Any, Tuple, Optional, List
 
@@ -203,6 +205,12 @@ def meos_get_intervalstyle() -> str:
 
 
 def meos_initialize(tz_str: "Optional[str]") -> None:
+    if "PROJ_DATA" not in os.environ and "PROJ_LIB" not in os.environ:
+        # Assume we are in a wheel and the PROJ data is in the package
+        proj_dir = os.path.join(os.path.dirname(__file__), "proj_data")
+        os.environ["PROJ_DATA"] = proj_dir
+        os.environ["PROJ_LIB"] = proj_dir
+
     tz_str_converted = tz_str.encode("utf-8") if tz_str is not None else _ffi.NULL
     _lib.meos_initialize(tz_str_converted, _lib.py_error_handler)
 
diff --git a/pymeos_cffi/setup.py b/pymeos_cffi/setup.py
index 8d234f42..7681da29 100644
--- a/pymeos_cffi/setup.py
+++ b/pymeos_cffi/setup.py
@@ -1,7 +1,37 @@
+import os
+import shutil
+
 from setuptools import setup
 
+
+package_data = []
+
+# Conditionally copy PROJ DATA to make self-contained wheels
+if os.environ.get("PACKAGE_DATA"):
+    print("Copying PROJ data to package data")
+    projdatadir = os.environ.get(
+        "PROJ_DATA", os.environ.get("PROJ_LIB", "/usr/local/share/proj")
+    )
+    if os.path.exists(projdatadir):
+        shutil.rmtree("pymeos_cffi/proj_data", ignore_errors=True)
+        shutil.copytree(
+            projdatadir,
+            "pymeos_cffi/proj_data",
+            ignore=shutil.ignore_patterns("*.txt", "*.tif"),
+        )  # Don't copy .tiff files and their related .txt files
+    else:
+        raise FileNotFoundError(
+            f"PROJ data directory not found at {projdatadir}. "
+            f"Unable to generate self-contained wheel."
+        )
+    package_data.append("proj_data/*")
+else:
+    print("Not copying PROJ data to package data")
+
 setup(
     packages=["pymeos_cffi", "pymeos_cffi.builder"],
     setup_requires=["cffi"],
+    include_package_data=True,
+    package_data={"pymeos_cffi": package_data},
     cffi_modules=["pymeos_cffi/builder/build_pymeos.py:ffibuilder"],
 )