diff --git a/tensorrt_llm/_torch/disaggregation/nixl/_agent_py.py b/tensorrt_llm/_torch/disaggregation/nixl/_agent_py.py
index dcfa28210f81..0b6a52d93de0 100644
--- a/tensorrt_llm/_torch/disaggregation/nixl/_agent_py.py
+++ b/tensorrt_llm/_torch/disaggregation/nixl/_agent_py.py
@@ -1,14 +1,33 @@
+import importlib
 import time
 from enum import Enum
 
-from nixl import nixl_agent, nixl_agent_config, nixl_xfer_handle
-
 from tensorrt_llm._utils import nvtx_range
 from tensorrt_llm.logger import logger
 
 # Import base classes for type compatibility
 from ..base.agent import BaseTransferAgent, RegMemoryDescs, TransferRequest, TransferStatus
 
+# The PyPI ``nixl`` meta-package provides a top-level ``nixl`` shim that
+# redirects to ``nixl_cu13`` or ``nixl_cu12``. When only ``nixl-cu13`` (or
+# ``nixl-cu12``) is installed without the meta-package, ``import nixl`` fails.
+# Try the CUDA-specific packages first, then fall back to the meta-package.
+_nixl_mod = None
+for _candidate in ("nixl_cu13", "nixl_cu12", "nixl"):
+    try:
+        _nixl_mod = importlib.import_module(_candidate)
+        break
+    except ImportError:
+        continue
+if _nixl_mod is None:
+    raise ImportError(
+        "Could not find a NIXL Python package. "
+        "Install ``nixl-cu13`` (CUDA 13) or ``nixl-cu12`` (CUDA 12)."
+    )
+nixl_agent = _nixl_mod.nixl_agent
+nixl_agent_config = _nixl_mod.nixl_agent_config
+nixl_xfer_handle = _nixl_mod.nixl_xfer_handle
+
 
 class TransferState(Enum):
     PENDING = "PENDING"
diff --git a/tests/integration/test_lists/waives.txt b/tests/integration/test_lists/waives.txt
index 1c7cd90dc257..a2f897f2e29a 100644
--- a/tests/integration/test_lists/waives.txt
+++ b/tests/integration/test_lists/waives.txt
@@ -351,7 +351,6 @@ unittest/auto_deploy/singlegpu/models/test_qwen3_5_moe.py::test_vlm_wrapper_delt
 unittest/auto_deploy/singlegpu/smoke/test_ad_build_small_single.py::test_build_ad[deepseek-ai/DeepSeek-V3-llm_extra_args10] SKIP (https://nvbugs/5888827)
 unittest/auto_deploy/standalone/test_standalone_package.py::TestStandalonePackage::test_run_unit_tests SKIP (https://nvbugs/6160629)
 unittest/bindings/test_transfer_agent_bindings.py::TestNixlFunctionalTransfer::test_nixl_wait_in_progress_on_zero_timeout SKIP (https://nvbugs/6260897)
-unittest/disaggregated/test_agent_multi_backends.py::test_run_with_different_env[1] SKIP (https://nvbugs/5979673)
 unittest/executor/test_rpc.py::TestRpcCorrectness::test_incremental_task_async SKIP (https://nvbugs/5741476)
 unittest/executor/test_rpc_proxy.py SKIP (https://nvbugs/5605741)
 unittest/executor/test_rpc_worker.py SKIP (https://nvbugs/5605741)