Validation runs of strelka2.
A sequenced mixture dataset of two Genome in a Bottle samples simulating a lower frequency set of calls. It has a 90x tumor genome consisting of 30% NA12878 (tumor) and 70% NA24385 (germline) and a 30x normal genome of NA24385. Unique NA12878 variants are somatic variations at 15% and 30%. This is a WGS dataset subset to examine genome wide exome regions along with all of chromosome 20.
Versions:
- GRCh37 genome build
- Strelka 2.8.2
- GATK4.0b5
- FreeBayes 1.1.0.46
- VarDict 1.5.1