diff --git a/.changeset/plenty-comics-matter.md b/.changeset/plenty-comics-matter.md
new file mode 100644
index 00000000000..77d26075a25
--- /dev/null
+++ b/.changeset/plenty-comics-matter.md
@@ -0,0 +1,5 @@
+---
+'@clerk/clerk-expo': patch
+---
+
+Use a polyfill for the `atob` function to prevent errors when using the Hermes JS engine, since the engine's `atob` implementation is stricter than it should be.
diff --git a/packages/expo/src/polyfills/base64Polyfill.ts b/packages/expo/src/polyfills/base64Polyfill.ts
index 960046fa0da..b36d38f63f2 100644
--- a/packages/expo/src/polyfills/base64Polyfill.ts
+++ b/packages/expo/src/polyfills/base64Polyfill.ts
@@ -1,9 +1,14 @@
 import { decode, encode } from 'base-64';
 
-if (!global.btoa) {
+//@ts-expect-error HermesInternal is added by the Hermes JS Engine
+const isHermes = !!global.HermesInternal;
+
+// See Default Expo 51 engine Hermes' issue: https://github.com/facebook/hermes/issues/1379
+if (!global.btoa || isHermes) {
   global.btoa = encode;
 }
 
-if (!global.atob) {
+// See Default Expo 51 engine Hermes' issue: https://github.com/facebook/hermes/issues/1379
+if (!global.atob || isHermes) {
   global.atob = decode;
 }