diff --git a/deepmd/pt/utils/auto_batch_size.py b/deepmd/pt/utils/auto_batch_size.py
index 5f8e0930d3..306d722fad 100644
--- a/deepmd/pt/utils/auto_batch_size.py
+++ b/deepmd/pt/utils/auto_batch_size.py
@@ -49,20 +49,54 @@ def is_oom_error(self, e: Exception) -> bool:
         e : Exception
             Exception
         """
-        # several sources think CUSOLVER_STATUS_INTERNAL_ERROR is another out-of-memory error,
-        # such as https://github.com/JuliaGPU/CUDA.jl/issues/1924
-        # (the meaningless error message should be considered as a bug in cusolver)
-        if (
-            isinstance(e, RuntimeError)
-            and (
-                "CUDA out of memory." in e.args[0]
-                or "CUDA driver error: out of memory" in e.args[0]
-                or "cusolver error: CUSOLVER_STATUS_INTERNAL_ERROR" in e.args[0]
-                # https://github.com/deepmodeling/deepmd-kit/issues/4594
-                or "CUDA error: out of memory" in e.args[0]
-            )
-        ) or isinstance(e, torch.cuda.OutOfMemoryError):
-            # Release all unoccupied cached memory
+        if isinstance(e, torch.cuda.OutOfMemoryError):
             torch.cuda.empty_cache()
             return True
+
+        if not isinstance(e, RuntimeError):
+            return False
+
+        # Gather messages from the exception itself and its chain.  AOTInductor
+        # (.pt2) sometimes strips the underlying OOM message when rewrapping,
+        # but not always; checking ``__cause__`` / ``__context__`` catches the
+        # remaining cases when the original error is preserved.
+        msgs: list[str] = []
+        cur: BaseException | None = e
+        seen: set[int] = set()
+        while cur is not None and id(cur) not in seen:
+            seen.add(id(cur))
+            if cur.args:
+                first = cur.args[0]
+                if isinstance(first, str):
+                    msgs.append(first)
+            cur = cur.__cause__ or cur.__context__
+
+        # Several sources treat CUSOLVER_STATUS_INTERNAL_ERROR as an OOM, e.g.
+        # https://github.com/JuliaGPU/CUDA.jl/issues/1924
+        # https://github.com/deepmodeling/deepmd-kit/issues/4594
+        plain_oom_markers = (
+            "CUDA out of memory.",
+            "CUDA driver error: out of memory",
+            "CUDA error: out of memory",
+            "cusolver error: CUSOLVER_STATUS_INTERNAL_ERROR",
+        )
+        if any(m in msg for msg in msgs for m in plain_oom_markers):
+            torch.cuda.empty_cache()
+            return True
+
+        # AOTInductor (.pt2) wraps the underlying CUDA OOM as a generic
+        # ``run_func_(...) API call failed at .../model_container_runner.cpp``.
+        # The original "CUDA out of memory" text is printed to stderr only and
+        # is absent from the Python-level RuntimeError, so we match on the
+        # wrapper signature.  If the root cause turns out to be something
+        # other than OOM, ``execute()`` will keep shrinking the batch and
+        # eventually raise ``OutOfMemoryError`` at batch size 1, which is a
+        # clean failure rather than an uncaught exception.
+        aoti_wrapped = any(
+            "run_func_(" in msg and "model_container_runner" in msg for msg in msgs
+        )
+        if aoti_wrapped:
+            torch.cuda.empty_cache()
+            return True
+
         return False
diff --git a/source/tests/pt/test_auto_batch_size.py b/source/tests/pt/test_auto_batch_size.py
index c67a23df52..e7bb69b62e 100644
--- a/source/tests/pt/test_auto_batch_size.py
+++ b/source/tests/pt/test_auto_batch_size.py
@@ -1,5 +1,8 @@
 # SPDX-License-Identifier: LGPL-3.0-or-later
 import unittest
+from unittest import (
+    mock,
+)
 
 import numpy as np
 
@@ -9,6 +12,36 @@
 
 
 class TestAutoBatchSize(unittest.TestCase):
+    @mock.patch("deepmd.pt.utils.auto_batch_size.torch.cuda.empty_cache")
+    def test_is_oom_error_cuda_message(self, empty_cache) -> None:
+        auto_batch_size = AutoBatchSize(256, 2.0)
+
+        self.assertTrue(
+            auto_batch_size.is_oom_error(RuntimeError("CUDA out of memory."))
+        )
+        empty_cache.assert_called_once()
+
+    @mock.patch("deepmd.pt.utils.auto_batch_size.torch.cuda.empty_cache")
+    def test_is_oom_error_empty_runtime_error_from_cuda_oom(self, empty_cache) -> None:
+        auto_batch_size = AutoBatchSize(256, 2.0)
+        cause = RuntimeError("CUDA driver error: out of memory")
+        error = RuntimeError()
+        error.__cause__ = cause
+
+        self.assertTrue(auto_batch_size.is_oom_error(error))
+        empty_cache.assert_called_once()
+
+    @mock.patch("deepmd.pt.utils.auto_batch_size.torch.cuda.empty_cache")
+    def test_is_oom_error_aoti_wrapper(self, empty_cache) -> None:
+        auto_batch_size = AutoBatchSize(256, 2.0)
+        error = RuntimeError(
+            "run_func_(...) API call failed at "
+            "/tmp/torchinductor/model_container_runner.cpp"
+        )
+
+        self.assertTrue(auto_batch_size.is_oom_error(error))
+        empty_cache.assert_called_once()
+
     def test_execute_all(self) -> None:
         dd0 = np.zeros((10000, 2, 1, 3, 4))
         dd1 = np.ones((10000, 2, 1, 3, 4))