diff --git a/src/coreclr/jit/importercalls.cpp b/src/coreclr/jit/importercalls.cpp
index 603cd256109134..8a8c96c7cfe44c 100644
--- a/src/coreclr/jit/importercalls.cpp
+++ b/src/coreclr/jit/importercalls.cpp
@@ -4112,22 +4112,31 @@ GenTree* Compiler::impIntrinsic(CORINFO_CLASS_HANDLE    clsHnd,
             }
 #endif // defined(TARGET_ARM64) || defined(TARGET_RISCV64)
 
-#if defined(TARGET_XARCH) || defined(TARGET_ARM64) || defined(TARGET_RISCV64)
+#if defined(TARGET_64BIT) || defined(TARGET_X86)
             // TODO-ARM-CQ: reenable treating InterlockedCmpXchg32 operation as intrinsic
             case NI_System_Threading_Interlocked_CompareExchange:
             {
+#if defined(TARGET_LOONGARCH64)
+                // GT_CMPXCHG is NYI in lsraloongarch64
+                mustExpand = false;
+                break;
+#endif
+
                 var_types retType = JITtype2varType(sig->retType);
 
                 if (genTypeSize(retType) > TARGET_POINTER_SIZE)
                 {
                     break;
                 }
-#if !defined(TARGET_XARCH) && !defined(TARGET_ARM64)
+#if defined(TARGET_RISCV64)
+                // CAS for small types is natively supported starting with the Zabha extension; however,
+                // hardware support for RVA23 profile is not available at the time of writing.
                 else if (genTypeSize(retType) < 4)
                 {
+                    mustExpand = false;
                     break;
                 }
-#endif // !defined(TARGET_XARCH) && !defined(TARGET_ARM64)
+#endif // defined(TARGET_RISCV64)
 
                 if ((retType == TYP_REF) &&
                     (impStackTop(1).val->IsIntegralConst(0) || impStackTop(1).val->IsIconHandle(GTF_ICON_OBJ_HDL)))
@@ -4158,18 +4167,27 @@ GenTree* Compiler::impIntrinsic(CORINFO_CLASS_HANDLE    clsHnd,
             case NI_System_Threading_Interlocked_Exchange:
             case NI_System_Threading_Interlocked_ExchangeAdd:
             {
+#if defined(TARGET_LOONGARCH64)
+                // GT_XADD and GT_XCHG are NYI in lsraloongarch64
+                mustExpand = false;
+                break;
+#endif
+
                 var_types retType = JITtype2varType(sig->retType);
 
                 if (genTypeSize(retType) > TARGET_POINTER_SIZE)
                 {
                     break;
                 }
-#if !defined(TARGET_XARCH) && !defined(TARGET_ARM64)
+#if defined(TARGET_RISCV64)
+                // CAS for small types is natively supported starting with the Zabha extension; however,
+                // hardware support for RVA23 profile is not available at the time of writing.
                 else if (genTypeSize(retType) < 4)
                 {
+                    mustExpand = false;
                     break;
                 }
-#endif // !defined(TARGET_XARCH) && !defined(TARGET_ARM64)
+#endif // defined(TARGET_RISCV64)
 
                 if ((retType == TYP_REF) &&
                     (impStackTop().val->IsIntegralConst(0) || impStackTop().val->IsIconHandle(GTF_ICON_OBJ_HDL)))
@@ -4199,7 +4217,7 @@ GenTree* Compiler::impIntrinsic(CORINFO_CLASS_HANDLE    clsHnd,
                                           callType, op1, op2);
                 break;
             }
-#endif // defined(TARGET_XARCH) || defined(TARGET_ARM64) || defined(TARGET_RISCV64)
+#endif // defined(TARGET_64BIT) || defined(TARGET_X86)
 
             case NI_System_Threading_Interlocked_MemoryBarrier:
             {