diff --git a/src/coreclr/jit/instr.cpp b/src/coreclr/jit/instr.cpp
index 9876150b22e35e..2fc259b0921566 100644
--- a/src/coreclr/jit/instr.cpp
+++ b/src/coreclr/jit/instr.cpp
@@ -163,7 +163,7 @@ const char* CodeGen::genInsDisplayName(emitter::instrDesc* id)
 
     auto GetIntCmpOpName = [&](const char* suffix) -> const char* {
         static const char* const intCmpOpNames[] = {
-            "eq", "lt", "le", "neq", "false", "ge", "gt", "true",
+            "eq", "lt", "le", "false", "neq", "ge", "gt", "true",
         };
 
         uint8_t control = static_cast<uint8_t>(emit->emitGetInsSC(id));
diff --git a/src/coreclr/tools/Common/TypeSystem/IL/Stubs/RuntimeHelpersIntrinsics.cs b/src/coreclr/tools/Common/TypeSystem/IL/Stubs/RuntimeHelpersIntrinsics.cs
index 0ce9a5267bb92b..7ec96db0eb5fbb 100644
--- a/src/coreclr/tools/Common/TypeSystem/IL/Stubs/RuntimeHelpersIntrinsics.cs
+++ b/src/coreclr/tools/Common/TypeSystem/IL/Stubs/RuntimeHelpersIntrinsics.cs
@@ -3,6 +3,7 @@
 
 using System;
 
+using Internal.Text;
 using Internal.TypeSystem;
 
 using Debug = System.Diagnostics.Debug;
@@ -56,9 +57,7 @@ public static MethodIL EmitIL(MethodDesc method)
                         result = false;
                         if (elementType is MetadataType mdType)
                         {
-                            if (mdType.Module == mdType.Context.SystemModule &&
-                                mdType.Namespace == "System.Text"u8 &&
-                                mdType.Name == "Rune"u8)
+                            if (IsKnownBitwiseEquatableType(mdType))
                             {
                                 result = true;
                             }
@@ -88,5 +87,21 @@ public static MethodIL EmitIL(MethodDesc method)
 
             return new ILStubMethodIL(method, new byte[] { (byte)opcode, (byte)ILOpcode.ret }, Array.Empty<LocalVariableDefinition>(), Array.Empty<object>());
         }
+
+        private static bool IsKnownBitwiseEquatableType(MetadataType type)
+        {
+            if (type.Module != type.Context.SystemModule)
+            {
+                return false;
+            }
+
+            Utf8Span ns = type.Namespace;
+            if (ns == "System"u8)
+            {
+                Utf8Span name = type.Name;
+                return name == "Guid"u8 || name == "Int128"u8 || name == "UInt128"u8;
+            }
+            return ns == "System.Text"u8 && type.Name == "Rune"u8;
+        }
     }
 }
diff --git a/src/coreclr/vm/jitinterface.cpp b/src/coreclr/vm/jitinterface.cpp
index 75197f0ddd4087..b8da06980a880c 100644
--- a/src/coreclr/vm/jitinterface.cpp
+++ b/src/coreclr/vm/jitinterface.cpp
@@ -7347,8 +7347,11 @@ static bool getILIntrinsicImplementationForRuntimeHelpers(
             || methodTable == CoreLibBinder::GetClass(CLASS__UINT32)
             || methodTable == CoreLibBinder::GetClass(CLASS__INT64)
             || methodTable == CoreLibBinder::GetClass(CLASS__UINT64)
+            || methodTable == CoreLibBinder::GetClass(CLASS__INT128)
+            || methodTable == CoreLibBinder::GetClass(CLASS__UINT128)
             || methodTable == CoreLibBinder::GetClass(CLASS__INTPTR)
             || methodTable == CoreLibBinder::GetClass(CLASS__UINTPTR)
+            || methodTable == CoreLibBinder::GetClass(CLASS__GUID)
             || methodTable == CoreLibBinder::GetClass(CLASS__RUNE)
             || methodTable->IsEnum()
             || IsBitwiseEquatable(typeHandle, methodTable))