version: 1.2 workflows: # ============================================================================= # PIPELINES - Complete analysis workflows combining multiple modules # ============================================================================= - name: ww-bwa-gatk subclass: WDL primaryDescriptorPath: /pipelines/ww-bwa-gatk/ww-bwa-gatk.wdl readMePath: /pipelines/ww-bwa-gatk/README.md testParameterFiles: - /pipelines/ww-bwa-gatk/inputs.json authors: - name: Emma Bishop email: ebishop@fredhutch.org role: Research Informatics Data Scientist affiliation: Fred Hutch Cancer Center orcid: 0000-0003-4484-3336 description: "WDL workflow to align sequencing data using BWA and perform QC steps with GATK" topic: variant-calling filters: branches: - main tags: - genomics - alignment - variant-calling - bwa - gatk - name: ww-ena-star subclass: WDL primaryDescriptorPath: /pipelines/ww-ena-star/ww-ena-star.wdl readMePath: /pipelines/ww-ena-star/README.md testParameterFiles: - /pipelines/ww-ena-star/inputs.json authors: - name: Taylor Firman email: tfirman@fredhutch.org role: Research Informatics Data Scientist affiliation: Fred Hutch Cancer Center orcid: 0009-0002-2052-1084 description: "WDL workflow to download raw sequencing data from ENA and align using STAR two-pass methodology" topic: rna-seq filters: branches: - main tags: - genomics - rna-seq - alignment - star - ena - name: ww-fastq-to-cram subclass: WDL primaryDescriptorPath: /pipelines/ww-fastq-to-cram/ww-fastq-to-cram.wdl readMePath: /pipelines/ww-fastq-to-cram/README.md testParameterFiles: - /pipelines/ww-fastq-to-cram/inputs.json authors: - name: Taylor Firman email: tfirman@fredhutch.org role: Research Informatics Data Scientist affiliation: Fred Hutch Cancer Center orcid: 0009-0002-2052-1084 - name: Emma Bishop email: ebishop@fredhutch.org role: Research Informatics Data Scientist affiliation: Fred Hutch Cancer Center orcid: 0000-0003-4484-3336 description: "Convert paired FASTQ files to unmapped CRAM format using WILDS WDL modules" topic: alignment filters: branches: - main tags: - genomics - format-conversion - fastq - cram - samtools - name: ww-imputation subclass: WDL primaryDescriptorPath: /pipelines/ww-imputation/ww-imputation.wdl readMePath: /pipelines/ww-imputation/README.md testParameterFiles: - /pipelines/ww-imputation/inputs.json authors: - name: Taylor Firman email: tfirman@fredhutch.org role: Research Informatics Data Scientist affiliation: Fred Hutch Cancer Center orcid: 0009-0002-2052-1084 - name: Emma Bishop email: ebishop@fredhutch.org role: Research Informatics Data Scientist affiliation: Fred Hutch Cancer Center orcid: 0000-0003-4484-3336 - name: Louisa Goss email: lgoss2@fredhutch.org role: Research Associate affiliation: Fred Hutch Cancer Center orcid: 0009-0005-2936-2405 description: "WDL workflow for genotype imputation from low-coverage WGS data using GLIMPSE2. Processes CRAM/BAM files against a reference panel to produce imputed VCF files." topic: imputation filters: branches: - main tags: - genomics - imputation - glimpse2 - low-coverage-wgs - genotyping - name: ww-jetlag subclass: WDL primaryDescriptorPath: /pipelines/ww-jetlag/ww-jetlag.wdl readMePath: /pipelines/ww-jetlag/README.md testParameterFiles: - /pipelines/ww-jetlag/inputs.json authors: - name: Taylor Firman email: tfirman@fredhutch.org role: Research Informatics Data Scientist affiliation: Fred Hutch Cancer Center orcid: 0009-0002-2052-1084 - name: Emma Bishop email: ebishop@fredhutch.org role: Research Informatics Data Scientist affiliation: Fred Hutch Cancer Center orcid: 0000-0003-4484-3336 - name: Caroline Nondin email: cnondin@fredhutch.org role: Research Assistant affiliation: Fred Hutch Cancer Center orcid: 0009-0009-0955-5954 description: "WDL pipeline to calculate sunrise/sunset times and sun time differences across an array of geographic tiles as part of the SJL model pipeline" topic: geospatial filters: branches: - main tags: - geospatial - solar-jetlag - environmental-health - sunrise-sunset - name: ww-leukemia subclass: WDL primaryDescriptorPath: /pipelines/ww-leukemia/ww-leukemia.wdl readMePath: /pipelines/ww-leukemia/README.md testParameterFiles: - /pipelines/ww-leukemia/inputs.json authors: - name: Taylor Firman email: tfirman@fredhutch.org role: Research Informatics Data Scientist affiliation: Fred Hutch Cancer Center orcid: 0009-0002-2052-1084 - name: Emma Bishop email: ebishop@fredhutch.org role: Research Informatics Data Scientist affiliation: Fred Hutch Cancer Center orcid: 0000-0003-4484-3336 - name: Sitapriya Moorthi email: smoorthi@fredhutch.org role: Staff Scientist affiliation: Fred Hutch Cancer Center orcid: 0000-0001-6372-5170 description: "Consensus variant calling workflow for human panel/PCR-based targeted DNA sequencing with focus on leukemia analysis - Refactored with WILDS modules" topic: variant-calling filters: branches: - main tags: - genomics - variant-calling - leukemia - targeted-sequencing - consensus-calling - name: ww-saturation subclass: WDL primaryDescriptorPath: /pipelines/ww-saturation/ww-saturation.wdl readMePath: /pipelines/ww-saturation/README.md testParameterFiles: - /pipelines/ww-saturation/inputs.json authors: - name: Taylor Firman email: tfirman@fredhutch.org role: Research Informatics Data Scientist affiliation: Fred Hutch Cancer Center orcid: 0009-0002-2052-1084 - name: Sitapriya Moorthi email: smoorthi@fredhutch.org role: Staff Scientist affiliation: Fred Hutch Cancer Center orcid: 0000-0001-6372-5170 - name: Siobhan O'Brien email: sobrien2@fredhutch.org role: Post-Doctoral Research Fellow affiliation: Fred Hutch Cancer Center description: "WDL workflow to analyze saturation mutagenesis data using BWA alignment and GATK AnalyzeSaturationMutagenesis" topic: saturation-mutagenesis filters: branches: - main tags: - genomics - saturation-mutagenesis - bwa - gatk - functional-genomics - name: ww-sra-salmon subclass: WDL primaryDescriptorPath: /pipelines/ww-sra-salmon/ww-sra-salmon.wdl readMePath: /pipelines/ww-sra-salmon/README.md testParameterFiles: - /pipelines/ww-sra-salmon/inputs.json authors: - name: Taylor Firman email: tfirman@fredhutch.org role: Research Informatics Data Scientist affiliation: Fred Hutch Cancer Center orcid: 0009-0002-2052-1084 - name: Emma Bishop email: ebishop@fredhutch.org role: Research Informatics Data Scientist affiliation: Fred Hutch Cancer Center orcid: 0000-0003-4484-3336 description: "WDL workflow to download raw sequencing data from SRA and quantify using Salmon quasi-mapping" topic: rna-seq filters: branches: - main tags: - genomics - rna-seq - quantification - salmon - sra - name: ww-sra-star subclass: WDL primaryDescriptorPath: /pipelines/ww-sra-star/ww-sra-star.wdl readMePath: /pipelines/ww-sra-star/README.md testParameterFiles: - /pipelines/ww-sra-star/inputs.json authors: - name: Taylor Firman email: tfirman@fredhutch.org role: Research Informatics Data Scientist affiliation: Fred Hutch Cancer Center orcid: 0009-0002-2052-1084 description: "WDL workflow to download raw sequencing data from SRA and align using STAR two-pass methodology" topic: rna-seq filters: branches: - main tags: - genomics - rna-seq - alignment - star - sra - name: ww-star-deseq2 subclass: WDL primaryDescriptorPath: /pipelines/ww-star-deseq2/ww-star-deseq2.wdl readMePath: /pipelines/ww-star-deseq2/README.md testParameterFiles: - /pipelines/ww-star-deseq2/inputs.json authors: - name: Taylor Firman email: tfirman@fredhutch.org role: Research Informatics Data Scientist affiliation: Fred Hutch Cancer Center orcid: 0009-0002-2052-1084 - name: Emma Bishop email: ebishop@fredhutch.org role: Research Informatics Data Scientist affiliation: Fred Hutch Cancer Center orcid: 0000-0003-4484-3336 - name: Ethan Bouvet email: ebouvet@fredhutch.org role: Research Technician affiliation: Fred Hutch Cancer Center description: "WDL workflow for RNA-seq alignment via STAR and DESeq2 differential expression analysis" topic: differential-expression filters: branches: - main tags: - genomics - rna-seq - differential-expression - star - deseq2 - name: ww-splicing-proteomics subclass: WDL primaryDescriptorPath: /pipelines/ww-splicing-proteomics/ww-splicing-proteomics.wdl readMePath: /pipelines/ww-splicing-proteomics/README.md testParameterFiles: - /pipelines/ww-splicing-proteomics/inputs.json authors: - name: Taylor Firman email: tfirman@fredhutch.org role: Research Informatics Data Scientist affiliation: Fred Hutch Cancer Center orcid: 0009-0002-2052-1084 description: "WDL pipeline for alternative splicing proteomics: STAR alignment, rMATS differential splicing detection, and JCAST protein sequence translation" topic: proteogenomics filters: branches: - main tags: - genomics - proteogenomics - alternative-splicing - rmats - jcast - star