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# Molecular-convergence-between-Down-syndrome-and-Fragile-X-syndrome-hPSCs
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Code repository for the paper "Molecular convergence between Down syndrome and Fragile X syndrome identified using human pluripotent stem cell models"
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* RNAseq folder contains all the RNAseq analysis.
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* Sequencing files were processed with [bcbio](https://bcbio-nextgen.readthedocs.io/en/latest/) using genome GRCh38_90.
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Output was summarized using [bcbioLite](https://github.com/vbarrera/bcbioLite) and stored in RNAseq/data as a [summarizedExperiment](https://bioconductor.org/packages/release/bioc/html/SummarizedExperiment.html).
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* RNAseq/QC: Quality control reports.
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* RNAseq/DE: Differential Expression analysis reports.
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<a href="https://zenodo.org/badge/latestdoi/238786320"><img src="https://zenodo.org/badge/238786320.svg" alt="DOI"></a>
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