diff --git a/docs/ext/pymysql/pymysql.rst b/docs/ext/pymysql/pymysql.rst
new file mode 100644
index 00000000000..23dca80c4f2
--- /dev/null
+++ b/docs/ext/pymysql/pymysql.rst
@@ -0,0 +1,7 @@
+OpenTelemetry PyMySQL Integration
+=================================
+
+.. automodule:: opentelemetry.ext.pymysql
+    :members:
+    :undoc-members:
+    :show-inheritance:
diff --git a/ext/opentelemetry-ext-dbapi/src/opentelemetry/ext/dbapi/__init__.py b/ext/opentelemetry-ext-dbapi/src/opentelemetry/ext/dbapi/__init__.py
index 441434b1897..7a94b58957f 100644
--- a/ext/opentelemetry-ext-dbapi/src/opentelemetry/ext/dbapi/__init__.py
+++ b/ext/opentelemetry-ext-dbapi/src/opentelemetry/ext/dbapi/__init__.py
@@ -178,6 +178,9 @@ def get_connection_attributes(self, connection):
         self.name = self.database_component
         self.database = self.connection_props.get("database", "")
         if self.database:
+            # PyMySQL encodes names with utf-8
+            if hasattr(self.database, "decode"):
+                self.database = self.database.decode(errors="ignore")
             self.name += "." + self.database
         user = self.connection_props.get("user")
         if user is not None:
diff --git a/ext/opentelemetry-ext-docker-tests/tests/pymysql/test_pymysql_functional.py b/ext/opentelemetry-ext-docker-tests/tests/pymysql/test_pymysql_functional.py
new file mode 100644
index 00000000000..e4ee65af30f
--- /dev/null
+++ b/ext/opentelemetry-ext-docker-tests/tests/pymysql/test_pymysql_functional.py
@@ -0,0 +1,108 @@
+# Copyright The OpenTelemetry Authors
+#
+# Licensed under the Apache License, Version 2.0 (the "License");
+# you may not use this file except in compliance with the License.
+# You may obtain a copy of the License at
+#
+#     http://www.apache.org/licenses/LICENSE-2.0
+#
+# Unless required by applicable law or agreed to in writing, software
+# distributed under the License is distributed on an "AS IS" BASIS,
+# WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+# See the License for the specific language governing permissions and
+# limitations under the License.
+
+import os
+import time
+import unittest
+
+import pymysql as pymy
+
+from opentelemetry import trace as trace_api
+from opentelemetry.ext.pymysql import trace_integration
+from opentelemetry.sdk.trace import Tracer, TracerProvider
+from opentelemetry.sdk.trace.export import SimpleExportSpanProcessor
+from opentelemetry.sdk.trace.export.in_memory_span_exporter import (
+    InMemorySpanExporter,
+)
+
+MYSQL_USER = os.getenv("MYSQL_USER ", "testuser")
+MYSQL_PASSWORD = os.getenv("MYSQL_PASSWORD ", "testpassword")
+MYSQL_HOST = os.getenv("MYSQL_HOST ", "localhost")
+MYSQL_PORT = int(os.getenv("MYSQL_PORT ", "3306"))
+MYSQL_DB_NAME = os.getenv("MYSQL_DB_NAME ", "opentelemetry-tests")
+
+
+class TestFunctionalPyMysql(unittest.TestCase):
+    @classmethod
+    def setUpClass(cls):
+        cls._connection = None
+        cls._cursor = None
+        cls._tracer_provider = TracerProvider()
+        cls._tracer = Tracer(cls._tracer_provider, None)
+        cls._span_exporter = InMemorySpanExporter()
+        cls._span_processor = SimpleExportSpanProcessor(cls._span_exporter)
+        cls._tracer_provider.add_span_processor(cls._span_processor)
+        trace_integration(cls._tracer_provider)
+        cls._connection = pymy.connect(
+            user=MYSQL_USER,
+            password=MYSQL_PASSWORD,
+            host=MYSQL_HOST,
+            port=MYSQL_PORT,
+            database=MYSQL_DB_NAME,
+        )
+        cls._cursor = cls._connection.cursor()
+
+    @classmethod
+    def tearDownClass(cls):
+        if cls._connection:
+            cls._connection.close()
+
+    def setUp(self):
+        self._span_exporter.clear()
+
+    def validate_spans(self):
+        spans = self._span_exporter.get_finished_spans()
+        self.assertEqual(len(spans), 2)
+        for span in spans:
+            if span.name == "rootSpan":
+                root_span = span
+            else:
+                db_span = span
+            self.assertIsInstance(span.start_time, int)
+            self.assertIsInstance(span.end_time, int)
+        self.assertIsNotNone(root_span)
+        self.assertIsNotNone(db_span)
+        self.assertEqual(root_span.name, "rootSpan")
+        self.assertEqual(db_span.name, "mysql.opentelemetry-tests")
+        self.assertIsNotNone(db_span.parent)
+        self.assertEqual(db_span.parent.name, root_span.name)
+        self.assertIs(db_span.kind, trace_api.SpanKind.CLIENT)
+        self.assertEqual(db_span.attributes["db.instance"], MYSQL_DB_NAME)
+        self.assertEqual(db_span.attributes["net.peer.name"], MYSQL_HOST)
+        self.assertEqual(db_span.attributes["net.peer.port"], MYSQL_PORT)
+
+    def test_execute(self):
+        """Should create a child span for execute
+        """
+        with self._tracer.start_as_current_span("rootSpan"):
+            self._cursor.execute("CREATE TABLE IF NOT EXISTS test (id INT)")
+        self.validate_spans()
+
+    def test_executemany(self):
+        """Should create a child span for executemany
+        """
+        with self._tracer.start_as_current_span("rootSpan"):
+            data = ["1", "2", "3"]
+            stmt = "INSERT INTO test (id) VALUES (%s)"
+            self._cursor.executemany(stmt, data)
+        self.validate_spans()
+
+    def test_callproc(self):
+        """Should create a child span for callproc
+        """
+        with self._tracer.start_as_current_span("rootSpan"), self.assertRaises(
+            Exception
+        ):
+            self._cursor.callproc("test", ())
+            self.validate_spans()
diff --git a/ext/opentelemetry-ext-mysql/setup.cfg b/ext/opentelemetry-ext-mysql/setup.cfg
index 3da2aad0f01..0b592641ce3 100644
--- a/ext/opentelemetry-ext-mysql/setup.cfg
+++ b/ext/opentelemetry-ext-mysql/setup.cfg
@@ -41,6 +41,7 @@ package_dir=
 packages=find_namespace:
 install_requires =
     opentelemetry-api == 0.7.dev0
+    opentelemetry-ext-dbapi == 0.7.dev0
     mysql-connector-python ~= 8.0
     wrapt >= 1.0.0, < 2.0.0
 
diff --git a/ext/opentelemetry-ext-pymysql/CHANGELOG.md b/ext/opentelemetry-ext-pymysql/CHANGELOG.md
new file mode 100644
index 00000000000..1512c421622
--- /dev/null
+++ b/ext/opentelemetry-ext-pymysql/CHANGELOG.md
@@ -0,0 +1,3 @@
+# Changelog
+
+## Unreleased
diff --git a/ext/opentelemetry-ext-pymysql/README.rst b/ext/opentelemetry-ext-pymysql/README.rst
new file mode 100644
index 00000000000..3cf845366b9
--- /dev/null
+++ b/ext/opentelemetry-ext-pymysql/README.rst
@@ -0,0 +1,24 @@
+OpenTelemetry PyMySQL integration
+=================================
+
+|pypi|
+
+.. |pypi| image:: https://badge.fury.io/py/opentelemetry-ext-pymysql.svg
+   :target: https://pypi.org/project/opentelemetry-ext-pymysql/
+
+Integration with PyMySQL that supports the PyMySQL library and is
+specified to trace_integration using 'PyMySQL'.
+
+
+Installation
+------------
+
+::
+
+    pip install opentelemetry-ext-pymysql
+
+
+References
+----------
+* `OpenTelemetry PyMySQL Integration <https://opentelemetry-python.readthedocs.io/en/latest/ext/pymysql/pymysql.html>`_
+* `OpenTelemetry Project <https://opentelemetry.io/>`_
diff --git a/ext/opentelemetry-ext-pymysql/setup.cfg b/ext/opentelemetry-ext-pymysql/setup.cfg
new file mode 100644
index 00000000000..9f44953a402
--- /dev/null
+++ b/ext/opentelemetry-ext-pymysql/setup.cfg
@@ -0,0 +1,48 @@
+# Copyright The OpenTelemetry Authors
+#
+# Licensed under the Apache License, Version 2.0 (the "License");
+# you may not use this file except in compliance with the License.
+# You may obtain a copy of the License at
+#
+#     http://www.apache.org/licenses/LICENSE-2.0
+#
+# Unless required by applicable law or agreed to in writing, software
+# distributed under the License is distributed on an "AS IS" BASIS,
+# WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+# See the License for the specific language governing permissions and
+# limitations under the License.
+#
+[metadata]
+name = opentelemetry-ext-pymysql
+description = OpenTelemetry PyMySQL integration
+long_description = file: README.rst
+long_description_content_type = text/x-rst
+author = OpenTelemetry Authors
+author_email = cncf-opentelemetry-contributors@lists.cncf.io
+url = https://github.com/open-telemetry/opentelemetry-python/tree/master/ext/opentelemetry-ext-pymysql
+platforms = any
+license = Apache-2.0
+classifiers =
+    Development Status :: 4 - Beta
+    Intended Audience :: Developers
+    License :: OSI Approved :: Apache Software License
+    Programming Language :: Python
+    Programming Language :: Python :: 3
+    Programming Language :: Python :: 3.4
+    Programming Language :: Python :: 3.5
+    Programming Language :: Python :: 3.6
+    Programming Language :: Python :: 3.7
+    Programming Language :: Python :: 3.8
+
+[options]
+python_requires = >=3.4
+package_dir=
+    =src
+packages=find_namespace:
+install_requires =
+    opentelemetry-api == 0.7.dev0
+    opentelemetry-ext-dbapi == 0.7.dev0
+    PyMySQL ~=  0.9.3
+
+[options.packages.find]
+where = src
diff --git a/ext/opentelemetry-ext-pymysql/setup.py b/ext/opentelemetry-ext-pymysql/setup.py
new file mode 100644
index 00000000000..a3f057b310b
--- /dev/null
+++ b/ext/opentelemetry-ext-pymysql/setup.py
@@ -0,0 +1,26 @@
+# Copyright The OpenTelemetry Authors
+#
+# Licensed under the Apache License, Version 2.0 (the "License");
+# you may not use this file except in compliance with the License.
+# You may obtain a copy of the License at
+#
+#     http://www.apache.org/licenses/LICENSE-2.0
+#
+# Unless required by applicable law or agreed to in writing, software
+# distributed under the License is distributed on an "AS IS" BASIS,
+# WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+# See the License for the specific language governing permissions and
+# limitations under the License.
+import os
+
+import setuptools
+
+BASE_DIR = os.path.dirname(__file__)
+VERSION_FILENAME = os.path.join(
+    BASE_DIR, "src", "opentelemetry", "ext", "pymysql", "version.py"
+)
+PACKAGE_INFO = {}
+with open(VERSION_FILENAME) as f:
+    exec(f.read(), PACKAGE_INFO)
+
+setuptools.setup(version=PACKAGE_INFO["__version__"])
diff --git a/ext/opentelemetry-ext-pymysql/src/opentelemetry/ext/pymysql/__init__.py b/ext/opentelemetry-ext-pymysql/src/opentelemetry/ext/pymysql/__init__.py
new file mode 100644
index 00000000000..0f06578e0bc
--- /dev/null
+++ b/ext/opentelemetry-ext-pymysql/src/opentelemetry/ext/pymysql/__init__.py
@@ -0,0 +1,68 @@
+# Copyright The OpenTelemetry Authors
+#
+# Licensed under the Apache License, Version 2.0 (the "License");
+# you may not use this file except in compliance with the License.
+# You may obtain a copy of the License at
+#
+#     http://www.apache.org/licenses/LICENSE-2.0
+#
+# Unless required by applicable law or agreed to in writing, software
+# distributed under the License is distributed on an "AS IS" BASIS,
+# WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+# See the License for the specific language governing permissions and
+# limitations under the License.
+
+"""
+The integration with PyMySQL supports the `PyMySQL`_ library and is specified
+to ``trace_integration`` using ``'PyMySQL'``.
+
+.. _PyMySQL: https://pypi.org/project/PyMySQL/
+
+Usage
+-----
+
+.. code:: python
+
+    import pymysql
+    from opentelemetry import trace
+    from opentelemetry.ext.pymysql import trace_integration
+    from opentelemetry.sdk.trace import TracerProvider
+
+    trace.set_tracer_provider(TracerProvider())
+    trace_integration()
+    cnx = pymysql.connect(database="MySQL_Database")
+    cursor = cnx.cursor()
+    cursor.execute("INSERT INTO test (testField) VALUES (123)"
+    cnx.commit()
+    cursor.close()
+    cnx.close()
+
+API
+---
+"""
+
+import typing
+
+import pymysql
+
+from opentelemetry.ext.dbapi import wrap_connect
+from opentelemetry.ext.pymysql.version import __version__
+from opentelemetry.trace import TracerProvider, get_tracer
+
+
+def trace_integration(tracer_provider: typing.Optional[TracerProvider] = None):
+    """Integrate with the PyMySQL library.
+       https://github.com/PyMySQL/PyMySQL/
+    """
+
+    tracer = get_tracer(__name__, __version__, tracer_provider)
+
+    connection_attributes = {
+        "database": "db",
+        "port": "port",
+        "host": "host",
+        "user": "user",
+    }
+    wrap_connect(
+        tracer, pymysql, "connect", "mysql", "sql", connection_attributes
+    )
diff --git a/ext/opentelemetry-ext-pymysql/src/opentelemetry/ext/pymysql/version.py b/ext/opentelemetry-ext-pymysql/src/opentelemetry/ext/pymysql/version.py
new file mode 100644
index 00000000000..86c61362ab5
--- /dev/null
+++ b/ext/opentelemetry-ext-pymysql/src/opentelemetry/ext/pymysql/version.py
@@ -0,0 +1,15 @@
+# Copyright The OpenTelemetry Authors
+#
+# Licensed under the Apache License, Version 2.0 (the "License");
+# you may not use this file except in compliance with the License.
+# You may obtain a copy of the License at
+#
+#     http://www.apache.org/licenses/LICENSE-2.0
+#
+# Unless required by applicable law or agreed to in writing, software
+# distributed under the License is distributed on an "AS IS" BASIS,
+# WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+# See the License for the specific language governing permissions and
+# limitations under the License.
+
+__version__ = "0.7.dev0"
diff --git a/ext/opentelemetry-ext-pymysql/tests/__init__.py b/ext/opentelemetry-ext-pymysql/tests/__init__.py
new file mode 100644
index 00000000000..e69de29bb2d
diff --git a/ext/opentelemetry-ext-pymysql/tests/test_pymysql_integration.py b/ext/opentelemetry-ext-pymysql/tests/test_pymysql_integration.py
new file mode 100644
index 00000000000..c452c31ec6d
--- /dev/null
+++ b/ext/opentelemetry-ext-pymysql/tests/test_pymysql_integration.py
@@ -0,0 +1,38 @@
+# Copyright The OpenTelemetry Authors
+#
+# Licensed under the Apache License, Version 2.0 (the "License");
+# you may not use this file except in compliance with the License.
+# You may obtain a copy of the License at
+#
+#     http://www.apache.org/licenses/LICENSE-2.0
+#
+# Unless required by applicable law or agreed to in writing, software
+# distributed under the License is distributed on an "AS IS" BASIS,
+# WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+# See the License for the specific language governing permissions and
+# limitations under the License.
+
+from unittest import mock
+
+import pymysql
+
+import opentelemetry.ext.pymysql
+from opentelemetry.ext.pymysql import trace_integration
+from opentelemetry.test.test_base import TestBase
+
+
+class TestPyMysqlIntegration(TestBase):
+    def test_trace_integration(self):
+        with mock.patch("pymysql.connect"):
+            trace_integration()
+            cnx = pymysql.connect(database="test")
+            cursor = cnx.cursor()
+            query = "SELECT * FROM test"
+            cursor.execute(query)
+
+        spans_list = self.memory_exporter.get_finished_spans()
+        self.assertEqual(len(spans_list), 1)
+        span = spans_list[0]
+
+        # Check version and name in span's instrumentation info
+        self.check_span_instrumentation_info(span, opentelemetry.ext.pymysql)
diff --git a/tox.ini b/tox.ini
index dc7f20aa8d1..e0c4314bc07 100644
--- a/tox.ini
+++ b/tox.ini
@@ -64,6 +64,10 @@ envlist =
     py3{4,5,6,7,8}-test-ext-pymongo
     pypy3-test-ext-pymongo
 
+    ; opentelemetry-ext-pymysql
+    py3{4,5,6,7,8}-test-ext-pymysql
+    pypy3-test-ext-pymysql
+
     ; opentelemetry-ext-wsgi
     py3{4,5,6,7,8}-test-ext-wsgi
     pypy3-test-ext-wsgi
@@ -120,6 +124,7 @@ changedir =
   test-ext-prometheus: ext/opentelemetry-ext-prometheus/tests
   test-ext-pymongo: ext/opentelemetry-ext-pymongo/tests
   test-ext-psycopg2: ext/opentelemetry-ext-psycopg2/tests
+  test-ext-pymysql: ext/opentelemetry-ext-pymysql/tests
   test-ext-wsgi: ext/opentelemetry-ext-wsgi/tests
   test-ext-zipkin: ext/opentelemetry-ext-zipkin/tests
   test-ext-flask: ext/opentelemetry-ext-flask/tests
@@ -171,6 +176,9 @@ commands_pre =
   psycopg2: pip install {toxinidir}/ext/opentelemetry-ext-dbapi
   psycopg2: pip install {toxinidir}/ext/opentelemetry-ext-psycopg2
 
+  pymysql: pip install {toxinidir}/ext/opentelemetry-ext-dbapi
+  pymysql: pip install {toxinidir}/ext/opentelemetry-ext-pymysql
+
   http-requests: pip install {toxinidir}/ext/opentelemetry-ext-http-requests[test]
 
   jaeger: pip install {toxinidir}/ext/opentelemetry-ext-jaeger
@@ -232,6 +240,7 @@ deps =
   thrift
   pymongo
   flask
+  pymysql
   mysql-connector-python
   wrapt
   psycopg2-binary
@@ -268,6 +277,7 @@ deps =
   docker-compose >= 1.25.2
   mysql-connector-python ~=  8.0
   pymongo ~= 3.1
+  pymysql ~= 0.9.3
   psycopg2-binary ~= 2.8.4
 
 changedir =
@@ -280,7 +290,8 @@ commands_pre =
               -e {toxinidir}/ext/opentelemetry-ext-dbapi \
               -e {toxinidir}/ext/opentelemetry-ext-mysql \
               -e {toxinidir}/ext/opentelemetry-ext-psycopg2 \
-              -e {toxinidir}/ext/opentelemetry-ext-pymongo
+              -e {toxinidir}/ext/opentelemetry-ext-pymongo \
+              -e {toxinidir}/ext/opentelemetry-ext-pymysql
   docker-compose up -d
   python check_availability.py
 commands =