diff --git a/Include/internal/pycore_critical_section.h b/Include/internal/pycore_critical_section.h
index 2b49b9f00df3ea..942bcff7e01df7 100644
--- a/Include/internal/pycore_critical_section.h
+++ b/Include/internal/pycore_critical_section.h
@@ -195,10 +195,9 @@ _PyCriticalSection2_Begin(PyCriticalSection2 *c, PyObject *a, PyObject *b)
 static inline void
 _PyCriticalSection2_End(PyCriticalSection2 *c)
 {
-    // if mutex1 is NULL, we used the fast path in
-    // _PyCriticalSection_BeginSlow for mutexes that are already held,
-    // which should only happen when mutex1 and mutex2 were the same mutex,
-    // and mutex2 should also be NULL.
+    // if mutex1 is NULL, we used the fast path in either
+    // _PyCriticalSection_BeginSlow or _PyCriticalSection2_BeginSlow for mutexes
+    // that are already held, and mutex2 should also be NULL.
     if (c->_cs_base._cs_mutex == NULL) {
         assert(c->_cs_mutex2 == NULL);
         return;
diff --git a/Misc/NEWS.d/next/Core_and_Builtins/2026-06-08-13-14-42.gh-issue-150902.-CWZ66.rst b/Misc/NEWS.d/next/Core_and_Builtins/2026-06-08-13-14-42.gh-issue-150902.-CWZ66.rst
new file mode 100644
index 00000000000000..e3b7cd387b439f
--- /dev/null
+++ b/Misc/NEWS.d/next/Core_and_Builtins/2026-06-08-13-14-42.gh-issue-150902.-CWZ66.rst
@@ -0,0 +1 @@
+Apply an existing optimization of PyCriticalSection (single mutex) to PyCriticalSection2: avoid acquiring the same locks that the current CS has already acquired.
diff --git a/Python/critical_section.c b/Python/critical_section.c
index 11a3f027547f39..d3df5caddae6d0 100644
--- a/Python/critical_section.c
+++ b/Python/critical_section.c
@@ -74,6 +74,22 @@ _PyCriticalSection2_BeginSlow(PyCriticalSection2 *c, PyMutex *m1, PyMutex *m2,
         c->_cs_base._cs_prev = 0;
         return;
     }
+    // Same optimization as in _PyCriticalSection_BeginSlow: skip locking when
+    // recursively acquiring the same locks.
+    if (tstate->critical_section &&
+        tstate->critical_section & _Py_CRITICAL_SECTION_TWO_MUTEXES) {
+        PyCriticalSection2 *prev2 = (PyCriticalSection2 *)
+            untag_critical_section(tstate->critical_section);
+        assert((uintptr_t)m1 < (uintptr_t)m2);
+        assert((uintptr_t)prev2->_cs_base._cs_mutex <
+            (uintptr_t)prev2->_cs_mutex2);
+        if (prev2->_cs_base._cs_mutex == m1 && prev2->_cs_mutex2 == m2) {
+            c->_cs_base._cs_mutex = NULL;
+            c->_cs_mutex2 = NULL;
+            c->_cs_base._cs_prev = 0;
+            return;
+        }
+    }
     c->_cs_base._cs_mutex = NULL;
     c->_cs_mutex2 = NULL;
     c->_cs_base._cs_prev = tstate->critical_section;