Thank you for this contribution !
To make it work using Python 3.10.9 I had to use pip instead of the provided setup.py:
cd pjsip-apps/src/
git clone https://github.com/mgwilliams/python3-pjsip.git
cd python3-pjsip
python setup.py build
pip install .
..otherwise I would always end up with the following error :
ImportError: /usr/local/python-3.10.9/lib/python3.10/site-packages/_pjsua.so: undefined symbol: pjsuaStart