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stephkoest/README.md

Stephan Köstlbacher

Hi, I’m Stephan – an evolutionary biologist and bioinformatics scientist based in Vienna. I specialize in phylogenomics, comparative genomics, and AI-driven biology. My work bridges evolutionary insights and big data, from protein structures to genome evolution, mostly using Python, R, and modern workflow tools.

  • Current: Scientific Computing Specialist @ AITHYRA (Austrian Academy of Sciences)
  • Pet project: @stephkoest/witchi – efficient detection and pruning of compositional bias in phylogenomic alignments.
  • Past life: Postdoc @ Wageningen University (NL), hunting eukaryotic ghosts in Asgard archaeal genomes. PhD @ University of Vienna, convincing people that Chlamydiae are not only interesting from a medical standpoint.
  • Background: Biologist by training, coder by necessity.
  • Interests: Structure-based protein discovery, the tree of life, functional genomics, and making sense of biological complexity with code and curiosity.
  • Fun fact: Either chasing hypertrophy or divine orbs in PoE2.
  • Connect:
    LinkedIn · Bluesky · GitHub

"Yeah, but can it be done anyways?"

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    A compositional bias testing and pruning tool for multiple sequence alignments

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