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computational-immunology

Here are 10 public repositories matching this topic...

Computational pipeline for antigen-specific tolerogenic vaccine design—predicting MHC-II epitopes, scoring tolerance potential, and assembling candidate multi-epitope mRNA constructs (starting with ITP).

  • Updated Apr 20, 2026
  • Jupyter Notebook

A multi-language bioinformatics pipeline (Bash, R, Python) for single-cell RNA-seq analysis of the Melanoma tumor microenvironment. Identifies CD8+ T-cell exhaustion signatures and statistically validates them as predictive biomarkers for Immune Checkpoint Blockade (ICB) therapy response.

  • Updated Mar 15, 2026
  • Python

MacroImmunet is a modular, event-driven research demo for agent-based simulation of immune responses at the tissue / organ scale. Rather than reproducing full single-cell biophysics, it explores how immune behavior emerges from structured coordination layers acting over spatial fields.

  • Updated Apr 6, 2026
  • Python

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